磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states.磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体 Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]

磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体Also known as:

RASGRP3 (phospho T133); p-RASGRP3 (phospho T133); Calcium and DAG-regulated guanine nucleotide exchange factor III; Grp3; GRP3_HUMAN; Guanine nucleotide exchange factor for Rap1; Kiaa0846; RAS guanyl releasing protein 3 (calcium and DAG regulated); RAS guanyl releasing protein 3 磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体calcium and DAG regualated guanine nucleotide exchange factor iii; Ras guanyl-releasing protein 3; RASGRP3

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human RASGRP3 around the phosphorylation site of Thr133.

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磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3抗体Predicted Molecular Weight: 78kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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