供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL12892R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml T淋巴细胞受体γ链2蛋白C抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not,T淋巴细胞受体γ链2蛋白C抗体 the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable) , J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional T淋巴细胞受体γ链2蛋白C抗体diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangment of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia.
T淋巴细胞受体γ链2蛋白C抗体Also known as:
T Cell Receptor V gamma 3; T cell rearranging gene gamma; T cell receptor gamma locus; T-cell receptor gamma chain C region PT-gamma-1/2; T-cell receptor gamma-2 chain C region; tcrg; TCRGC2; trg; TRGC2; TRGC2(2X); TRGC2(3X).
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated synthetic peptide derived from human TCRGC2.
●
Predicted Molecular Weight: 22kDa.
T淋巴细胞受体γ链2蛋白C抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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