胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体_价格

产品详情

胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体

英文名称 PDX1

中文名称胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体

别名 Glucose sensitive factor; Glucose-sensitive factor; GSF; IDX 1; IDX-1; IDX1; Insulin promoter factor 1; insulin promoter factor 1 homeodomain transcription factor; insulin upstream factor 1; IPF 1; IPF-1; IPF1; Islet/duodenum homeobox 1; Islet/duodenum homeobox-1; IUF 1; IUF-1; IUF1; MODY4; Pancreas/duodenum homeobox 1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox P; PDX 1; PDX-1; PDX1; PDX1_HUMAN; Somatostatin transactivating factor 1; Somatostatin-transactivating factor 1; STF 1; STF-1; STF1.

研究领域细胞生物神经生物学生长因子和激素转录调节因子内分泌病

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,

产品应用 Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 30kDa

细胞定位细胞核

性状 Lyophilized or Liquid

浓度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human PDX1:101-200/284

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed

产品介绍 The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

PDX1是一种同源框转录因子-即胰十二指肠同源异型盒基因，又称IPF-1(胰岛素促进因子)、IDX-1、IUF-1。
近年来，科学家们对PDX1从不同的角度进行了卓有成效的研究。有学者认为；PDX1是胰腺发育及胰岛素基因转录表达的关键性转录因子，即决定于胰腺前体细胞向B、A、D细胞的分化。
还有学者认为：PDX1对于肠内胚层背胰芽和腹胰芽的生长、分化起重要作用，早期胰腺表达的PDX-1对胰腺上皮的形成和分化是必需的。

胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体信息由上海联迈生物工程有限公司为您提供，如您想了解更多关于胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体报价、型号、参数等信息，欢迎来电或留言咨询。除供应胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体外，上海联迈生物工程有限公司还可为您提供粘着斑激酶抗体、凋亡抑制蛋白抗体等产品，公司有专业的客户服务团队，是您值得信赖的合作伙伴。

供货周期：	现货
品牌：	LMAI Bio
规格：	50ul/100ul/200ul
货号：	LM20738R
CAS号：