爱必信(absin) abs50001 Annexin V-FITC/PI细胞凋亡检测试剂盒,好用不贵、受到越来越多老师们的认可,使用该产品发表在各类优质期刊上的文献已经多达52篇啦!
1、 产品原理及应用
细胞凋亡早期,位于细胞膜脂质双层内侧的磷脂酰丝氨酸PS会从细胞膜内侧翻转到细胞膜的表面,而钙离子依赖型的Annexin V可与PS特异性结合;PI不能透过完整的细胞膜,凋亡中晚期细胞膜通透性增加、PI 得以透过细胞膜而使细胞核染红。
将Annexin V-FITC 与PI 配合使用,可以有效区分处于不同凋亡时期的细胞。
abs50001 Annexin V-FITC/PI细胞凋亡检测试剂盒既适用于流式细胞仪的定量研究,也可用于原位染色的定性研究。
2、 产品优势
1) 简便:只需分别加缓冲液、Annexin V-FITC和PI即可;
2) 快捷:从加缓冲液到上机只需20分钟;
3) 灵敏:与荧光染料法等相比灵敏度更高、特异性更强。
abs50001 Annexin V-FITC/PI细胞凋亡检测试剂盒与其他同类型产品相比,可有效减少流式实验时早期凋亡细胞与正常细胞的黏连情况,且非特异性结合较少、分群更为清晰。
3、 文献展示
实验结果图 [图片来源于文献内容】
Three macrophage subsets are identified in the uterus during early human pregnancy
Cell Mol Immunol. 2018 Apr 04 ; 12
影响因子: 8.483
Enzyme-instructed self-aggregation of Fe3O4 nanoparticles for enhanced MRI T2 imaging and photothermal therapy of tumors
Nanoscale. 2020 Jan 06 .
影响因子: 6.97
The apoptosis of MCF-7 cells after incubating with different liposomes for 48 h.
Tyrosine modified irinotecan-loaded liposomes capable of simultaneously targeting LAT1 and ATB0,+ for efficient tumor therapy J Control Release. 2019 Oct 30 .
影响因子: 7.901
Moderate mechanical stress suppresses the IL‐1β‐induced chondrocyte apoptosis by regulating mitochondrial dynamics
Journal of Cellular Physiology. 2021 Apr 06 .
影响因子: 5.547
Cimigenoside functions as a novel γ-secretase inhibitor and inhibits the proliferation or metastasis of human breast cancer cells by γ-secretase/Notch axis
Pharmacological Research. 2021 Feb 20 .
影响因子: 5.894
4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo
Acta Pharmacologica Sinica. 2020 Dec 11 .
影响因子: 5.064
lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca2+ overload in myocardial infarction mice model
Cell Death & Disease. 2019 Dec 09 .
影响因子: 6.303
Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors
EUR J MED CHEM. 2019 Nov 22 .
影响因子: 5.573
MRI-visible and pH-sensitive micelles loaded with doxorubicin for hepatoma treatment
Biomaterials Science. 2019 Mar 26 ; 4
影响因子: 6.18
Codelivery of sorafenib and GPC3 siRNA with PEI-modified liposomes for hepatoma therapy
Biomaterials science. 2017 Dec 23 ; 12
影响因子: 6.184
产品信息:
货号 | 名称 | 规格 |
abs50001 | Annexin V-FITC/PI细胞凋亡检测试剂盒 | 25T/20T/100T |
abs50005 | PI细胞周期与凋亡试剂盒 | 50T |
abs50006 | Annexin V-EGFP/PI Apoptosis analysis kit | 20T/50T |
abs50007 | Annexin V-PE/7-AAD apoptosis analysis kit | 25T/100T |
abs50008 | Annexin V-APC/7-AAD apoptosis analysis kit | 25T/100T |
abs50033 | TUNEL细胞凋亡检测试剂盒-FITC | 20T/50T |
Absin特色产品线(全部现货):
爱必信(上海)生物科技有限公司 联系邮箱:info@absin.cn 公众平台:爱必信生物 |
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