盐酸黄酮哌酯中有效成分含量检测方案(自动电位滴定)

智能文字提取功能测试中

TIC-98005enL京都电子工业株式会社-可睦电子(上海)商贸有限公司 上海市徐汇区宜山路333号1201室电话： 021-54488867 电邮： kemu-kem@163.com 网址： http：//www.kem-china.com-K-MKYOTO ELECTRONICSMANUFACTURING CO.，LTD. Application Memo Flavoxate Hydrochloride 1.Overview Flavoxate Hydrochloride is measured by titration with 0.1mL perchloric acid + acetic acidafter dissolving the sample in glacial acetic acid and acetonitrile and adding acetic anhydride.The endpoint is determined by the inflexion point on the titration curve. The concentration iscalculated from the titration volume of perchloric acid+ acetic acid. 2. Apparatus Main unit Automatic potentiometric titrator (preamplifier STD) Electrode pH glass electrode Double junction reference electrode Temperature compensation electrode 3. Reagents Titrant 0.1mol/L perchloric acid + acetic acidSolvent Glacial acetic acid， Acetonitrile， Acetic acid anhydride 4. Example Sample Titer Conc. (g) (mL) (%) 12 3 0.6090 14.2195 100.5 0.6011 14.0472 100.5 0.6068 14.1892 100.6 Average 100.5 0.07 0.07 SD RSD(%) -Titration curve- Please feel free to contact us for any further information. Kyoto Electronics Manufacturing Co.， Ltd.Overseas Sales & Marketing Sect. 盐酸黄酮哌酯含量测定 应用资料(英文版)根据中国药典2020年版，盐酸黄酮哌酯【含量测定】取本品约0.3g，精密称定，加冰醋酸5ml与乙腈20ml溶解后，加醋酐25ml，照电位滴定法（通则0701），用高氯酸滴定液（0.1mol/L）滴定，并将滴定结果用空白试验校正。每1ml高氯酸滴定液（0.1mol/L）相当于42.79mg的C24H25NO4·HCl。