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智能文字提取功能测试中
与传统的光学探测器相比,质谱仪提供分析物的质量信息,通常提供高灵敏度和选择性分析。近年来,在药品开发和其他各种行业中,它已被用作目标分析物的选择性检测和杂质鉴定的方法。超临界流体萃取(SFE)可以利用具有高扩散率、渗透率和溶解度等特定特性的超临界流体进行快速、高效的萃取。二氧化碳(二氧化碳)在中等条件下(超临界温度;31ºC,超临界压力;7.4 MPa)容易达到超临界状态,作为SFE的萃取溶剂得到广泛应用。采用超临界二氧化碳的SFE具有易于后萃取处理、溶剂成本低、装置控制自动化等优点。我们开发了一种结合SFE与制备SFC和质谱检测器的开关系统,在单一系统中提供MS触发器的提取、制备和纯化。在本报告中,我们将介绍利用该系统从咖啡豆中提取并制备分离和纯化咖啡因的应用。 Switching system of SFE/Prep SFC with MS detecto r Akitaka T earadal, Satoe lijima1, DJ Tognarelliz, John Burchell, Yasuyo Satol , Miki Kuwajima1 1JASCO Corporation, 2967-5 Ishikawa-machi, Hachioji, Tokyo 192-8537 2JASCO Incorporated, 28600 Mary's Court, Easton, MD 21601 E-mai l : satoe.iijima@jasco.co.jp Results and Discussion We determined the purity of extrac t s collec t ed in SFE by HPLC -PDA. Figure 9 shows the chromatograms of caffeine standard solution and concentrated extrac ts (mixture of ext r ac t ion 1 to 4) from sample 1. Figure 10shows the comparison of caffeine spectra between sta n da r d solution and s ample solut i on. A high corre l at i on coeff i cien t was obtained between them (>0.9995). Figure 11 a n d Table 3 show the resu l ts of peak pur i ty.98.8% of the peak wa s determined h i gh-pur i ty caffeine . 【System】 【Sample Preparation】 ac c ording t o t h e degrees o f correl a tion. Conclusion ●We ach i eved the extraction and fract i on collection o f caffe i ne from gree n coffee beans using a switch i ng system SFE/Prep SFC-MS. ●T he combination of PDA and MS detectors enables the detection a nd fraction collection of various compounds V with or wit h out a chromop h ore. ●ChromNAV softoware provides automatic and acc u rate fractions with advanced fraction algorithms, and useful f unctions (ex. fr action simulation, graphical display o f col l ec t ion mon i toring and results).
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佳士科商贸有限公司为您提供《SFE/Prep SFC开关系统》,该方案主要用于生物药品药物研发中分离、提纯、开关系统检测,参考标准《暂无》,《SFE/Prep SFC开关系统》用到的仪器有JASCO SFC4000超临界流体色谱仪、JASCO高效色谱仪LC-4000。
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