The Agilent Thermal Equilibration Device Increases Resolution for Oligonucleotide Analysis

检测样品 预防类生物药品

检测项目 含量测定

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Combining the Agilent 1290 Infinity II Bio LC System with the Agilent Thermal Equilibration Device for High‑Performance Oligonucleotide Analysis

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Due to advances in oligonucleotide synthesis and modification, modern DNA‑ or RNA‑based biopharmaceuticals can make characterization more demanding because of their increased complexity. This application note demonstrates that the Agilent Thermal Equilibration Device (TED) combined with the biocompatible Agilent 1290 Infinity II Bio LC is an excellent setup for in‑depth analysis of oligonucleotides. Using the TED with a high‑temperature LC method, the peak resolution and analysis speed can be significantly increased. Product and processimpurities can be separated and analyzed. These results show that oligonucleotide analysis can significantly benefit from the TED.

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安捷伦科技(中国)有限公司为您提供《The Agilent Thermal Equilibration Device Increases Resolution for Oligonucleotide Analysis》,该方案主要用于预防类生物药品中含量测定检测,参考标准《暂无》,《The Agilent Thermal Equilibration Device Increases Resolution for Oligonucleotide Analysis》用到的仪器有Agilent 1290 Infinity II 生物液相色谱系统 。

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