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【求助】哪位高手给介绍一下核磁技术在生物大分子方面的应用?

核磁共振技术(NMR)

  • 现在想了解一下有关核磁在生物大分子方面的应用文献,不知如何下手。哪位比较清楚,给个简要介绍(提纲就可以),我去查查有关方面的最新进展。
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  • celan

    第3楼2007/09/06

    NMR for biological molecules
    This 1 day course covers the set up and processing of experiments commonly used for structure determination of biological macromolecules. Discussions include spectrometer configurations, the calibration of pulses, parameter optimization, and acquisition of 3D experiments. Data processing of 3D data, including linear prediction, phase corrections, strip transforms, and baseline corrections will also be covered in this course.



    Experiments:
    2D Homo- and Heteronuclear Correlation Experiments (COSY, NOESY, 1H-15N HSQC, relaxation experiments)
    3D Experiments (NOESY-HSQC, TOCSY-HSQC and many triple resonance experiments HNCO, HNCACB, CBCA(CO)NH etc.)

    Prerequisite:
    This course will presume extensive experience with the spectrometer, an advanced knowledge of FT-NMR and multipulse, multidimensional techniques or attendance at the courses AVANCE - Liquids or NMR.2D.


    http://www.bruker-biospin.com/training_bio_nmr.html

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