方案摘要
方案下载| 应用领域 | 制药/生物制药 |
| 检测样本 | 预防类生物药品 |
| 检测项目 | 含量测定>色谱法 |
| 参考标准 | / |
Accurate analysis of riboflavin diphosphates and monophosphates with the Agilent 1290 Infinity II Bio LC System
Phosphated vitamin B2 (riboflavin) vitamers were analyzed by UHPLC and a performance comparison was made in terms of peak shape and recovery obtained on an Agilent 1290 Infinity II LC System (classic stainless steel LC) versus an Agilent 1290 Infinity II Bio LC System (biocompatible LC), and on classic versus metal-free column hardware. The results clearly demonstrate the necessity of biocompatible flow paths for accurate analysis of riboflavin diphosphates and monophosphates to prevent nonspecific interactions of these compounds
with the metal surfaces. The iron-free flow path allows the use of volatile MS/ELSD-compatible mobile phases for the direct analysis of the phosphorylated species without the need for enzymatic treatment with phosphatase.
文献贡献者
使用 Agilent 8697 顶空进样器和 8850 GC-FID 系统进行制药行业的残留溶剂分析
利用透射拉曼光谱对软凝胶胶囊进行定量与鉴定测试
检测婴儿配方奶粉、牛奶和鸡蛋中的 30 种全氟烷基和多氟烷基化合物
相关产品
CrossLab企业资产管理服务
Agilent GC 8890 气相色谱系统
Agilent Cary 3500 紫外可见分光光度计
Agilent Resolve 手持拉曼系统
Agilent TRS100 激光拉曼系统
Agilent 1290 Infinity II 二维液相色谱解决方案
Agilent 1290 Infinity II 液相色谱系统
Agilent 1260 Infinity II 液相色谱系统
Agilent 7900 电感耦合等离子体质谱仪
Agilent Bravo 自动液体处理平台
Agilent 7010C 三重四极杆气质联用系统
Agilent 7000E 三重四极杆气质联用系统
Agilent 5977C GC/MSD 单四极杆气质联用仪
Agilent 1290 Infinity II 高通量系统
Agilent 1290 Infinity II 方法转移系统
关注
拨打电话
留言咨询
