用于评价血小板活化和双瓣尖人工心脏瓣膜泄露导致的凝血趋势的新型体外流动系统研制

2008/06/15   下载量: 44

方案摘要

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应用领域 医疗/卫生
检测样本 全血/血清/血浆
检测项目
参考标准 暂无

Thromboembolic events caused by implanted cardiovascular devices present serious challenges to surgeons and researchers alike. In particular bileaflet mechanical heart valves are prone to thrombus formation in the hinge region due to a combination of high shear stress and stagnation regions. Shear-induced platelet activation and aggregation is usually studied using viscometers, parallel plate flow, and other non-physiologic in vitro configurations. However, it is desirable to study this phenomenon in a more physiological environment.

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