患者特异性脑动脉瘤血流动力学： 体外体视粒子成像测速，计算流体动力学（CFD）和体内4D流动磁共振成像（MRI）等方法的比较

2019/08/12   下载量： 1 次

方案摘要

方案下载
应用领域 医疗/卫生
检测样本 癌细胞/肿瘤细胞
检测项目
参考标准 暂无

采用LaVision的DaVis 10.0图像采集和处理软件平台，加上一台Nd-YLF 激光器 (Continuum Terra-PIV, l = 527 nm)以及四台高速相机(Phantom Miro)构成了一套4D3C抖盒子流场测量系统。并利用这套系统进行了患者特异性脑动脉瘤血流动力学研究，分析比较了 体外体视粒子成像测速，计算流体动力学（CFD）和体内4D流动磁共振成像（MRI）等方法。

方案下载
配置单
方案详情

    Typical approaches to patient-specific hemodynamic studies of cerebral aneurysms use image based computational fluid dynamics (CFD) and seek to statistically correlate parameters such as wall shear stress (WSS) and oscillatory shear index (OSI) to risk of growth and rupture. However, such studies have reported contradictory results, emphasizing
the need for in-depth comparisons of volumetric experiments and CFD. In this work, we conducted tomographic particle velocimetry experiments using two patient-specific cerebral aneurysm models (basilar tip and internal carotid artery) under pulsatile flow conditions and processed the particle images using Shake the Box (STB), a particle tracking method.
The STB data was compared to that obtained from in vivo 4D flow MRI and CFD. Although qualitative agreement of flow pathlines across modalities was observed, each modality maintained notably unique spatiotemporal distributions of low normalized WSS regions. Analysis of time averaged WSS (TAWSS), OSI, and Relative Residence Time (RRT)
demonstrated that non-dimensional parameters, such as OSI, may be more robust to the varying assumptions, limitations, and spatial resolutions of each subject and modality. These results suggest a need for further multi-modality analysis as well as development of non-dimensional hemodynamic parameters and correlation of such metrics to aneurysm risk of growth and rupture.

上一篇 在一个双稳湍流涡旋火焰中，对间歇性动态的时间-频率定位
下一篇 圆柱形颗粒尺寸的离散元法模型优化

文献贡献者

北京欧兰科技发展有限公司
金牌会员 丨 第17年
查看全部资料
相关仪器 更多
相关方案
更多

相关产品

当前位置： 欧兰科技 方案 患者特异性脑动脉瘤血流动力学： 体外体视粒子成像测速，计算流体动力学（CFD）和体内4D流动磁共振成像（MRI）等方法的比较

关注

拨打电话

留言咨询