ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA|Demeditec DE7170|96 Tests|DE7170-上海叶舟生物科技有限公司

产品详情

产品名称：ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA

产地：Demeditec

产品货号：DE7170

产品规格：96 Tests

产品说明：

Special remarks:

NAME AND INTENDED USE

ACPA is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against citrullinated Proteins (ACP), in human serum or plasma. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of rheumatoid arthritis.

SUMMARY AND EXPLANATION OF THE TEST

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. The main characteristics of RA is joint inflammation that results in joint damage and loss of function. An early diagnosis of RA and an immediate beginning of an appropriate treatment is important to prevent a complete joint damage.

RA is diagnosed primarily on clinical manifestations and serological suppport has, up to now, been mainly restricted to the determination of autoantibodies against rheumatoid factor (RF). RF is a sensitive serological marker for RA with a moderate specificity of about 70%. In several studies it has been demonstrated that the determination of antibodies against citrullinated arginine residues in filament proteins occurs in RF negative patients. Citrullination is an peptidylarginine deiminase (PAD) catalysed process in which the amino acid arginine (Arg) is modified to citrullin. During this conversion, the positively charged NH2-group is hydrolyzed to an oxygen group.

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ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA|Demeditec DE7170由上海叶舟生物科技有限公司为您提供，货号DE7170，规格：96 Tests，CAS号：，如您想了解更多关于ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA|Demeditec DE7170价格、ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA|Demeditec DE7170结构式、批发、用途等信息，欢迎咨询。除供应ACPA (Anti-Citrullinated Protein Antibodies) ELISAACPA (Anti-Citrullinated Protein Antibodies) ELISA|Demeditec DE7170外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海叶舟客户服务电话，售前、售后均可联系。

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