供货周期: | 7天 |
品牌: | Abcam |
型号: | 0.1ml/0.2ml |
货号: | 促销活动 |
Anti-SYVN1/HRD1抗体|滑膜细胞凋亡抑制物1抗体产品介绍:Synoviolin, also called HRD1, Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HD) or unfolded GPR37 by promoting their degradation. Sequesters TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis. Belongs to the HRD1 family.
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【产品名称】:Anti-SYVN1/HRD1抗体|滑膜细胞凋亡抑制物1抗体
【产品编号】:BYK-0679R
【规 格】:0.1ml/0.2ml
【相关标记】:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC
【产品别名】:1200010C09Rik; HRD1; KIAA1810; MGC40372; Synovial apoptosis inhibitor 1 synoviolin; Synoviolin 1 isoform b; SYVN1_HUMAN.
【浓 度】:1mg/1ml
【抗体来源】:Rabbit or Mouse or Goat
【克隆类型】:polyclonal or monoclonal
【产品类型】:一抗
【性 状】:Lyophilized or Liquid
【亚 型】:IgG
【纯化方法】:affinity purified by Protein A
【储 存 液】:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
【产品应用】:not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
【保存条件】:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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