Mouse Anti-CD16 antibody
ABCAM
Catalog Number : RS-9028R
Quantity size : 0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
background:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved
in the removal of antigen-antibody complexes from the circulation, as well as other other
antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby
gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed
on natural killer(NK) cells as an integral membrane glycoprotein anchored through a
transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear
neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI)
linkage. Mutations in this gene have been linked to susceptibility to recurrent viral
infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal
neutropenia. Alternatively spliced transcript variants encoding different isoforms have
been found for this gene. [provided by RefSeq, Jul 2008].
Specificity : · anti-CD16 is a mouse Polyclonal antibody, unconjugated
· specific for anti-CD16 of human, mouse and rat.
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt:27 kDa
– Application :
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100
IHC-P=1:100-500 IHC-F=1:100-500 FCM=1:100-500
Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized
antibody is stable at room temperature for at least one month and for greater than a year when kept
at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is
stable for at least two weeks at 2-4 oC.
Important Note: This product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
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