CD41抗体，CD41抗体说明书

上海瑞齐生物技术有限公司

2014/10/08 15:41

Rat Anti-CD41抗体，CD41抗体说明书antibody
ABCAM
Catalog Number : RS-2637R
Quantity size : 0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
background:
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer
and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single
disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3
subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on
platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen,
von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa
complex is the major Integrin on platelets and is important for platelet adhesion and
aggregation.
Specificity : · anti-CD41 is a rat Polyclonal antibody, unconjugated
· specific for anti-CD41 of human, mouse and rat.
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt：125 kDa
– Application :
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized
antibody is stable at room temperature for at least one month and for greater than a year when kept
at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is
stable for at least two weeks at 2-4 oC.
Important Note: This product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.

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