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【原创】QTOF 数据处理中Pareto Scaling 是什么意思?

液质联用(LCMS)

  • 请教各位, QTOF采集代谢数据后,用软件进行数据统计分析时的Pareto Scaling是哪一种数据处理模式? 敬请哪位大侠解释一下
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  • 活到九十 学到一百

    第1楼2008/04/15

    Pareto, 直条构成线图(又称佩尔托图)
    Scale, 尺度/量表

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  • dickwang2008

    第2楼2008/04/16

    我找人问了一哈,大概意思是“Pareto Scaling”是数据预处理的一种方法,简写“par”,就是将变量除以变量的方差的平方根。

    Ameng0608 发表:请教各位, QTOF采集代谢数据后,用软件进行数据统计分析时的Pareto Scaling是哪一种数据处理模式? 敬请哪位大侠解释一下

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  • liuyiming312

    第6楼2008/04/23

    Abstract—The notion of Pareto-optimality is one of the major
    approaches to multiobjective programming. While it is desirable
    to find more Pareto-optimal solutions, it is also desirable to find
    the ones scattered uniformly over the Pareto frontier in order to
    provide a variety of compromise solutions to the decision maker.
    In this paper, we design a genetic algorithm for this purpose. We
    compose multiple fitness functions to guide the search, where each
    fitness function is equal to a weighted sum of the normalized objective
    functions and we apply an experimental design method called
    uniform design to select the weights. As a result, the search directions
    guided by these fitness functions are scattered uniformly toward
    the Pareto frontier in the objective space. With multiple fitness
    functions, we design a selection scheme to maintain a good
    and diverse population. In addition, we apply the uniform design
    to generate a good initial population and design a new crossover
    operator for searching the Pareto-optimal solutions. The numerical
    results demonstrate that the proposed algorithm can find the
    Pareto-optimal solutions scattered uniformly over the Pareto frontier

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