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【求助】USP正文的含量测定中用到high-speed blender是个什么样的装置?在哪能买到?

  • summer0751
    2009/11/25
  • 私聊

中药/天然药检测

  • USP正文Valproic Acid Capsules的含量测定中用到a high-speed blender,用它把胶囊打碎后测定含量。不知道这是个什么样的装置,在哪里能买到?
    原文如下:Assay preparation— Transfer not fewer than 20 Capsules to a blender jar or other container, add about 150 mL of methylene chloride, and cool in a solid carbon dioxide-acetone mixture until the contents have solidified. If necessary, transfer the mixture of Capsules and methylene chloride to a blender jar, and blend with a high-speed blender until all the solids are reduced to fine particles. Transfer the mixture to a 500-mL volumetric flask, add n-heptane to volume, mix, and allow solids to settle. Transfer an accurately measured volume of this solution, equivalent to 250 mg of valproic acid, to a 100-mL volumetric flask, dilute with n-heptane to volume, and mix. Transfer 5.0 mL to a container equipped with a closure. Add 2.0 mL of Internal standard solution, close the container, and mix.

    还有很多品种的含量测定中用到high-speed glass blender,USP中是否有这种装置的介绍呢?我们想用,可不知道在哪里能查到,望知道的给指导下呀。
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  • 冷冷的冰雨

    第1楼2009/11/25

    http://www.cmrshop.cn/?product-72.html


    看看是不是!没用过,网上搜了搜

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  • summer0751

    第2楼2009/11/25

    我们试过两种匀浆机,它的刀头是钝的,靠的是硬力打碎。由于我们的药品是软胶囊,胶囊皮总是打不碎。
    我打电话去咨询下,谢谢xy4585618哦,辛苦了!
    因为USP的很多品种的样品处理方法都用到这种装置,不知是不是有专门的仪器?

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