SB 203580|SB203580|SB-203580|

SB 203580|SB203580|SB-203580|

参考价:¥1653
供货周期: 7天
品牌: Millipore
型号: 1MG
货号: 559389-1MG
CAS号: 152121-47-6
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产品编号: 559389-1MG     查看说明书
产品名称: 原装现货|SB 203580|SB203580|SB-203580|   订购此产品
供应商: Merck
规格: ***
目录价: 1653
库存状态: 现货
CAS编号: 152121-47-6
应用范围:  
种属来源:  
相关信息:

559389  SB 203580
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole
Reduces epirubicin-induced cell injury and caspase-3/7 activity. A highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 34 nM in vitro, 600 nM in cells). Does not significantly inhibit the JNK and p42 MAP kinase at 100 µM. Inhibits IL-1 and TNF-α production from LPS-stimulated human monocytes and the human monocyte cell line THP-1 (IC50 = 50-100 nM). Inhibits bone morphogenetic protein-2-induced neurite outgrowth in PC12 cells. Also inhibits platelet aggregation caused by collagen (IC50 = 0.2-1.0 µM) or the thromboxane analog U-46619 (Cat. No. 538944). A 1 mg/ml solution of SB 203580 (Cat. No. 559398) in anhydrous DMSO is also available.
Alternatives
559395  SB 203580, Hydrochloride 
559400  SB 203580, Iodo- 
Alternative products for SB 203580
559395  SB 203580, Hydrochloride 
559400  SB 203580, Iodo- 
Accessories for SB 203580
Product information 
Form  Thin film 
Primary Target  P38MAPK 
Primary Target IC50  34 nM 
Secondary target  THP-1 (IC50 = 500-100 nM) 
Molar mass  377.4 
Protect from Light  Yes 
Cell permeable  Yes 
Purity  ≥98% by HPLC 
Solubility  DMSO 
Chemical formula  C21H16N3OSF 
CAS number  152121-47-6 
Store and ship information 
Storage  -20°C 
Ship  Ambient Temperature Only
Irritant 
Safety information 
S Phrase  S: 26-36-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). 
R Phrase  R: 36/37/38
Irritating to eyes, respiratory system and skin. 

保存条件: -20度

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