LY 294002|LY294002|LY-294002

LY 294002|LY294002|LY-294002

参考价:¥2092
供货周期: 7天
品牌: Millipore
型号: 5MG
货号: 440202-5MG
CAS号: 154447-36-6
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产品编号: 440202-5MG     查看说明书
产品名称: 原装现货|LY 294002|LY294002|LY-294002   订购此产品
供应商: Merck
规格: ***
目录价: 2092
库存状态: 现货
CAS编号: 154447-36-6
应用范围:  
种属来源:  
相关信息:

440202  LY 294002
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
A cell-permeable, potent, reversible and specific phosphatidylinositol 3-kinase inhibitor (IC50 = 1.4 µM) that acts on the ATP-binding site of the enzyme. Also inhibits nonhomologous DNA end-joining (NHEJ) activity of the 460 kDa phosphatidylinositol 3-like kinase DNA-PKcs, which is the catalytic subunit of DNA-activated protein kinase. Does not affect the activities of EGF receptor kinase, MAP kinase, PKC, Pl 4-kinase, S6 kinase, and c-Src even at 50 µM. Blocks the proliferation of cultured rabbit aortic smooth muscle cells without inducing apoptosis. A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440204) in DMSO is also available.
Product information 
Form  Off-white solid 
Primary Target  specific phosphatidylinositol 3-kinase inhibitor 
Primary Target IC50  1.4 µM 
Molar mass  307.4 
Protect from Light  Yes 
Cell permeable  Yes 
Purity  ≥98% by HPLC 
Solubility  DMSO or EtOH 
Chemical formula  C19H17NO3 
CAS number  154447-36-6 
Store and ship information  
Storage  -20°C 
Ship  Ambient Temperature Only
Standard Handling 
 

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