PGT抗体说明书

Rabbit Anti-PGT抗体说明书
ABCAM

Cat. Number: Rs-014021R

Quantity size: 0.1ml (dilute with pH 7.4 0.01 M PBS or diluent of antibody)

Background: The organic anion transporting polypeptide (Oatp) family of proteins play a role in drug absorption, distribution and excretion. Oatp proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. OATP2A1, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or PGT (in both humans and rodents), is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, OATP2A1 is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding OATP2A1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine

receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Specificity: · anti-PGT is a rabbit monoclonal antibody unconjugated

· specific for PGT of human

· use for western blotting, elisa, immunoprecipitation

and immunohistochemistry

· Protein A affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 80 kDa

Application: · Western blotting: 1:100-500

· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Optimal working dilutions must be determined by the end user.

Storage: Store at –20 oC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20oC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 oC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.