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This study demonstrates a routine screening of drugs to identify and quantify potential genotoxic compounds. In this Application Note, we used an Agilent 6545 Q-TOF LC/MS system to acquire accurate mass data of samples containing chlorhexidine as the drug substance. Agilent MassHunter Mass Profi ler software was used to mine the data and compare different samples to generate a differential list of compounds. An accurate mass database search against the differential list identifi ed 4-chloroaniline, a potential genotoxic compound. All Ions MS/MS acquisition mode was used to confi rm 4-chloroaniline by MS/MS library matching, and quantify it using external standards. This workflow is suitable for batch-to-batch sample analysis for detecting and quantifying known potential genotoxic compounds
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安捷伦科技(中国)有限公司为您提供《遗传毒性化合物中遗传毒性检测方案(ICP-AES)》，该方案主要用于其他中遗传毒性检测，参考标准《暂无》，《遗传毒性化合物中遗传毒性检测方案(ICP-AES)》用到的仪器有null。
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