Automated UHPLC method development for mebendazole and related impurities, from method scouting to robustness testing

检测样品 化药新药研发

检测项目 含量测定

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ChromSword Chromeleon Connect, Vanquish Flex, mebendazole, impurity analysis, UHPLC, automated method development, robustness test.

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• The Thermo Scientific™ Vanquish™ UHPLC Method Development system in combination with ChromSword Chromeleon Connect enables automated and unattended method development. • The proposed method development workflow for the analysis of mebendazole and related impurities considerably reduces method development time and cost.• The complete workflow includes method scouting, method optimization, and method robustness testing.• The AutoRobust module of ChromSword Chromeleon Connect provides the robust region to afford assurance of quality of the final method via the design space between method parameters.

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赛默飞色谱与质谱为您提供《Automated UHPLC method development for mebendazole and related impurities, from method scouting to robustness testing》,该方案主要用于化药新药研发中含量测定检测,参考标准《暂无》,《Automated UHPLC method development for mebendazole and related impurities, from method scouting to robustness testing》用到的仪器有赛默飞 Vanquish Flex UHPLC系统。

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