本人在做的一种辅料中有一种杂质算是有药理毒性的，所以在定它的限量时遇到了问题，此限量不能太高，但定得太低了也没必要，我觉得定的高度要和此物质的药理活性或毒性有关，所以就拼命找它的毒理学实验数据，找到的那些资料的描写都是此物质“a very weak carcinogen”或与某某物质比它的毒性很低，但这并不能直接说明人体或动物对它能承受的剂量是多少，还有一些貌似是毒理学实验的表述如下： XXX was mutagenic in the Ames test, increasing the number of revertants to 4 to 9 times the control values in Salmonella typhimurium TA98, TA100, TA1535 and TA1538. The maximum effects were obtained with concentrations between 20 and 500 μg per plate . It could be shown in strain TA1535 that the mutagenicity was markedly reduced by the addition of S9 mix . XXX also yielded positive results in the cell transformation test in vitro (Syrian hamster kidney cells, human lung fibroblasts or human liver cells) and in the degranulation of the rough endoplasmic reticulum of isolated rat liver cells , in the sebaceous gland test on mouse skin and in the tetrazolium reduction test on mouse skin . (The relevance of these latter three tests is not clear.) In the host-mediated assay (mouse) XXX (106 mg/kg i.m. or 138 mg/kg p.o.) proved to be clearly mutagenic in the S. typhimurium strains TA1530, TA1535 and TA1538 . 这些在我看来都是一些实验数据，并不能明确的说明此物质的毒性在什么水平，有哪位大虾能帮忙解释一下这些数据的确切含义吗？ 另外，到目前为止我所找到关于此物质描述中有确切分类的是这句话 XXX is classified in Section III B of the MAK List
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