Abstract: Responsive hydrogels, also known as “smart hydrogels”, can be modified in different ways to respond to physical and chemical stimuli and microenvironment changes. Nowadays, responsive hydrogels have been widely used in biomedical fields, such as pH responsive hydrogel loaded with doxorubicin (DOX) for cancer treatment, temperature responsive hydrogels made from 3D printing for wound healing, glucose responsive hydrogels for diabetes treatment, etc. In this paper, we introduce the current research of responsive hydrogel, including the preparation and modification methods, applications in biomedicine and the future directions.
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