【求助】（已应助）求一篇英文文献

happyjyl

2008/06/17

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标题：Method development and validation for the HPLC assay (potency and related substances) for 20 mg paroxetine tablets

作者：John Lambropoulos, George A. Spanos and Nick V. Lazaridis

杂志：Journal of Pharmaceutical and Biomedical Analysis
Volume 19, Issue 5, April 1999, Pages 793-802

摘要：A reversed phase high performance liquid chromatographic (HPLC) method was developed and validated for use as a stability indicating assay (potency and related substances) of paroxetine in paroxetine hydrochloride 20 mg tablets. Assay samples were extracted at a paroxetine concentration of 0.4 mg ml−1 utilizing mobile phase as the extraction solvent. The chromatographic conditions employed a C18 column (Inertsil, 5 μm, 15 cm×4.6 mm), isocratic elution with 10 mM 1-decane sulfonic acid sodium salt containing 10 mM sodium phosphate monobasic (pH 3.0)–ACN (60:40, v/v) and ultraviolet (UV) detection at 235 nm.

网址：http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TGX-3VVTHD4-G&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=8147a4e72cb61be808de35f935fdc0f6

非常感谢！

littleshaobing 2008/06/17

[img]https://www.instrument.com.cn/bbs/images/affix.gif[/img][url=http://www.instrument.com.cn/bbs/download.asp?ID=93504]Method development and validation for the HPLC assay (potency and related substances) for 20 mg paroxetine tablets[/url]附件中是该文献

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