无机麦地
第1楼2011/05/19
看到这几点比较全面
Accurate molecular weight measurements:
sample confirmation, to determine the purity of a sample, to verify amino acid substitutions, to detect post-translational modifications, to calculate the number of disulphide bridges
Reaction monitoring:
to monitor enzyme reactions, chemical modification, protein digestion
Amino acid sequencing:
sequence confirmation, de novo characterisation of peptides, identification of proteins by database searching with a sequence "tag" from a proteolytic fragment
Oligonucleotide sequencing:
the characterisation or quality control of oligonucleotides
Protein structure:
protein folding monitored by H/D exchange, protein-ligand complex formation under physiological conditions, macromolecular structure determination
monod
第7楼2011/05/20
精确分子量测量;反应监测(液质常提到的MRM 多反应监测模式);氨基酸测序;寡核苷酸测序;蛋白质结构分析。