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高手帮我掰扯掰扯这句话是什么逻辑关系吧

  • fengmo4668
    2012/10/10
  • 私聊

专业英语

  • 看到这样的一段话,文献里面的,把我整晕了,有高手愿意帮我梳理一下,到底是怎么样的一个逻辑关系。
    谢谢啦!

    The sample size (20 patients for each group) was determined based on power calculations to detect inter-group
    differences in terms of clinical outcomes. The initial sample size consisted of 38 patients. After the exclusion of 8 patients
    (20%) the two study groups each consisted of 16 randomised hospital admissions, giving a total of 32 admissions for 30
    patients.

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  • smilefly110

    第1楼2012/10/11

    Sample size 20 patients for one group,
    At first, exclusion 8 patients (20%), i.e. total 40 patients, only 32 patients left.
    Two groups, each consists 16 admissions, i.e. total 32 admissions, but, only 30 patients participate?

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  • fengmo4668

    第2楼2012/10/11

    Only 30 patients,can have 32 admissions? How?

    smilefly110(smilefly110) 发表:Sample size 20 patients for one group,
    At first, exclusion 8 patients (20%), i.e. total 40 patients, only 32 patients left.
    Two groups, each consists 16 admissions, i.e. total 32 admissions, but, only 30 patients participate?

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  • 上海卓技

    第3楼2012/10/12

    the two study groups each consisted of 16 randomised hospital admissions

    randomised means使混乱

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  • poorlittle

    第4楼2012/10/13

    Randomized 随机的

    Typing error? giving a total of 32 admissions for 40 patients

    上海卓技(sh102151) 发表:the two study groups each consisted of 16 randomised hospital admissions

    randomised means使混乱

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  • poorlittle

    第5楼2012/10/13

    This may be a second study, the sample size may be 38 patients in the initial study. Or, the initial sample size was 38 patients in the planning stage, but the size of 40 patients was adopted as the designed (or determined) size in the study, therefore it may mean:

    The sample size (20 patients for each group, totally 40 patients although the initial sample size consisted of 38 patients) was determined based on power calculations to detect inter-group differences in terms of clinical outcomes.
    After the exclusion of 8 patients (20%) the two study groups each consisted of 16 randomised hospital admissions, giving a total of 32 admissions for 40 patients.

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  • happyjyl

    第6楼2012/10/27

    一开始根据统计学要求计算出的样本量:每组20个患者,两组共40个。[1]

    一开始实际入组的患者:38个。[2]

    随机化后剔除了8个不符合临床试验方案要求的患者。[3]

    理论上:方案要求受试者为住院患者[4]。一开始每组有20个随机的住院患者名额(admissions),两组共40个。试验开始后排除掉8个不符合方案要求的患者(占40个名额的20%),共还有32个名额,即每组16个。

    实际上:一开始只入组了38个患者,排除掉8个不符合方案要求的患者,实际完成试验的只有30个。最后的试验数据和结论是在这30个患者的临床试验结果上统计分析后得出的。

    [1] based on power calculations to detect inter-group differences in terms of clinical outcomes--临床结果应能检测出组间差异,并且该临床试验的把握度应符合要求。

    [2]由于入组时限、患者数量等限制,有时不能在规定时间内入组足够数量的患者。

    [3]见原文:The internal validity of the study results is questionable due to the small sample size and the fact that the analysis of the results was based on the principle of treatment completers, after the post-randomization exclusion of those patients who did not comply with the protocols.

    [4]见原文:The study patients were set to be able to start TEN or TPN within 48 hours of hospital admission, without having any evidence of short bowel syndrome, Crohn's disease or major pancreatic resection.

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  • fengmo4668

    第7楼2012/10/27

    多谢指点!
    还是有个疑问,既然是30个病人,又怎么可以做出来32份数据报告呢?

    happyjyl(happyjyl) 发表:一开始根据统计学要求计算出的样本量:每组20个患者,两组共40个。[1]

    一开始实际入组的患者:38个。[2]

    随机化后剔除了8个不符合临床试验方案要求的患者。[3]

    理论上:方案要求受试者为住院患者[4]。一开始每组有20个随机的住院患者名额(admissions),两组共40个。试验开始后排除掉8个不符合方案要求的患者(占40个名额的20%),共还有32个名额,即每组16个。

    实际上:一开始只入组了38个患者,排除掉8个不符合方案要求的患者,实际完成试验的只有30个。最后的试验数据和结论是在这30个患者的临床试验结果上统计分析后得出的。

    [1] based on power calculations to detect inter-group differences in terms of clinical outcomes--临床结果应能检测出组间差异,并且该临床试验的把握度应符合要求。

    [2]由于入组时限、患者数量等限制,有时不能在规定时间内入组足够数量的患者。

    [3]见原文:The internal validity of the study results is questionable due to the small sample size and the fact that the analysis of the results was based on the principle of treatment completers, after the post-randomization exclusion of those patients who did not comply with the protocols.

    [4]见原文:The study patients were set to be able to start TEN or TPN within 48 hours of hospital admission, without having any evidence of short bowel syndrome, Crohn's disease or major pancreatic resection.

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  • happyjyl

    第8楼2012/10/27

    请发全文。网上只有摘要,从摘要里看不出来有32份数据报告。感觉作者的逻辑不太好,有点颠三倒四的。

    fengmo4668(fengmo4668) 发表:多谢指点!
    还是有个疑问,既然是30个病人,又怎么可以做出来32份数据报告呢?

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  • fengmo4668

    第9楼2012/10/27

    “ the two study groups each consisted of 16 randomised hospital admissions, giving a total of 32 admissions for 30
    patients.“这段话里面不就是说30个病人32份报告吗?还提及是每组16份。

    happyjyl(happyjyl) 发表:请发全文。网上只有摘要,从摘要里看不出来有32份数据报告。感觉作者的逻辑不太好,有点颠三倒四的。

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  • poorlittle

    第10楼2012/10/28

    May be a typing error :

    giving a total of 32 admissions for 38 (patients actually involved)

    giving a total of 32 admissions for 40 (patients expected as determined based on power calculations)

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