1. Dear Dr. Defendi ML: I am sending a manuscript entitled “” by – which I should like to submit forpossible publication in the journal of - . Yours sincerely 2. Dear Dr. A: Enclosed is a manuscript entitled “” by sb, which we are submitting for publicationin the journal of - . We have chosen this journal because it deals with - . Webelieve that sth would be of interest to the journal’s readers. 3. Dear Dr.A: Please find enclosed for your review an original research article, “” by sb.All authors have read and approve this version of the article, and due care hasbeen taken to ensure the integrity of the work. No part of this paper haspublished or submitted elsewhere. No conflict of interest exits in thesubmission of this manuscript, and we have attached to this letter the signedletter granting us permission to use Figure 1 from another source. We appreciate your consideration of our manuscript, and we look forward toreceiving comments from the reviewers.