【Abstract】 Objective To establish a method for the content determination of trepibutone tablets by HPLC.Methods Diamonsil (TM) C18 column (250mm×4.6 mm,5μm) was adopted.The mobile phase was a mixture of pH=3.3 acetonitrile-0.01 mol/L potassium dihydrogen phosphate (60:40) and the flow rate was 1 mL/min.The detection wavelength was 235 nm.The temperature was set at 35℃.Results The calibration curve was good linear relationship in the range of 4-20μg/mL (r=0.999 9).The mean recovery rate was 100.5... 更多还原 【关键词】 高效液相色谱法; 曲匹布通; 含量测定; 【Key words】 HPLC; trepibutone; content determination;