【讨论】农残分析中LOD和LOQ的计算

有一个问题，在欧盟METHOD VALIDATION AND QUALITY CONTROL PROCEDURES FOR PESTICIDE RESIDUES ANALYSIS IN FOOD AND FEED 文件中，认为LOD与LOQ是一个东西--定量测定限，检出限用limit of detection 表示，LOD是limit of determination,原文释义如下：LOQ--Limit of quantitation (quantification) (also known as limit of determination, LOD). The minimum concentration or mass of the analyte that can be quantified with acceptable accuracy and precision. Should apply to the complete analytical method. Variously defined but must be a value greater than the limit of detection. With most methods and determination systems, the LOQ has no fixed value. LOQ is preferable to LOD because it avoids possible con-fusion with “limit of detection”. However, in legislation MRLs that are set at the limit of quantification/determination are referred to as “LOD MRLs”, not“LOQ MRLs”.