myreebok
第3楼2009/06/24
附录2 溶液颜色检查
按本药典规定,用下面两种方法之一可以检出溶液在棕色-黄色-红色范围内的颜色。
如果溶液A的外观与水或所用溶剂相同,或者颜色浅于标准比色液B9,则可判定溶液A为无色。
方法I
用外径为12mm的无色、透明中性玻璃管取2ml的供试溶液,与相同玻璃管中的2ml的水,或2ml本文所规定的标准比色液(见标准比色液表)进行比较。在散射自然光,白色的背景下,水平观察比较颜色。
方法Ⅱ
用同样平底、内径为15~25mm的无色透明中性玻璃管,液位的深度为40mm,将供试溶液与水或溶剂或本文中规定的标准比色液(见标准比色液表)对比。在散射自然光,白色的背景下,垂直地观察比较颜色。
贮备液
黄色液 称取46克氯化铁,加大约900ml盐酸溶液(25ml浓盐酸和975ml水混和)溶解,继续添加,并定容1000.0ml。
滴定并以上述盐酸溶液调整,使黄色液每毫升含45.0mg FeCl3﹒6H2O。避光保存。
滴定 在一个配有磨口塞的250ml锥形瓶内,加入10.0ml黄色液,15ml 水,5ml浓盐酸和4g碘化钾,塞上瓶塞,在暗处放置15分钟,再加100ml 水。用0.1M的硫代硫酸钠标准溶液滴定游离的碘,在滴定接近终点时加0.5ml淀粉试液作指示剂。
1ml 0.1M的硫代硫酸钠标准溶液相当于27.03mg FeCl3﹒6H2O。
红色液 称取60克氯化钴,加大约900ml盐酸溶液(25ml浓盐酸和975ml水混和)溶解,继续添加,并定容1000.0ml。
滴定并以上述盐酸溶液调整,使红色液每毫升含59.5mg CoCl2﹒6H2O。
滴定 在一个配有磨口塞的250ml锥形瓶内,加入5.0ml红色液,5ml稀过氧化氢溶液和10ml 300g/l的氢氧化钠溶液,缓慢煮沸10分钟,冷却后,加60ml稀硫酸和2g碘化钾,塞上瓶塞,缓慢摇动锥形瓶,使沉淀溶解完全。用0.1M的硫代硫酸钠标准溶液滴定游离的碘,在滴定接近终点时加入0.5ml淀粉试液作为指示剂。溶液变成粉红色时到达滴定终点。
1ml0.1M的硫代硫酸钠标准溶液相当于23.79mg CoCl2﹒6H2O。
蓝色液 称取63克硫酸铜加大约900ml盐酸溶液(25ml浓盐酸和975ml水混和)溶解,继续添加,并定容1000.0ml。
滴定并以上述盐酸溶液调整,使蓝色液每毫升含62.4mg CuSO4﹒5H2O。
滴定 在一个配有磨口塞的250ml锥形瓶内,加入10.0ml蓝色液,50ml水,12ml稀醋酸和3g碘化钾。用0.1M的硫代硫酸钠标准溶液滴定游离碘,在滴定接近终点时加入0.5ml淀粉试液作为指示剂。当溶液变为轻微的淡褐色时到达滴定终点。
1ml0.1M的硫代硫酸钠标准溶液相当于24.97mg CuSO4﹒5H2O。
颜色标准溶液
用3种贮备液制备5种颜色标准液。如表2-1。
表2-1,颜色标准液
标准溶液 黄色溶液 红色溶液 蓝色溶液 盐酸(10g/l)
B(褐色) 3.0 3.0 2.4 1.6
BY(黄褐色) 2.4 1.0 0.4 6.2
Y(黄色) 2.4 0.6 0.0 7.0
GY(黄绿色) 9.6 0.2 0.2 0.0
R(红色) 1.0 2.0 0.0 7.0
方法I和方法Ⅱ的标准比色液
用5种颜色标准溶液,制备以下各种颜色的标准比色液。
表2-2,标准比色液B
对照溶液 颜色标准溶液B 盐酸(10g/l)
B1 75.0 25.0
B2 50.0 50.0
B3 37.5 62.5
B4 25.0 75.0
B5 12.5 87.5
B6 5.0 95.0
B7 2.5 97.5
B8 1.5 98.5
B9 1.0 99.0
表2-3,标准比色液BY
对照溶液 颜色标准溶液BY 盐酸(10g/l)
BY1 100.0 0.0
BY2 75.0 25.0
BY3 50.0 50.0
BY4 25.0 75.0
BY5 12.5 87.5
BY6 5.0 95.0
BY7 2.5 97.5
表2-4,标准比色液Y
对照溶液 颜色标准溶液Y 盐酸(10g/l)
Y1 100.0 0.0
Y2 75.0 25.0
Y3 50.0 50.0
Y4 25.0 75.0
Y5 12.5 87.5
Y6 5.0 95.0
Y7 2.5 97.5
表2-5,标准比色液GY
对照溶液 颜色标准溶液GY 盐酸(10g/l)
GY1 100.0 75.0
GY2 75.0 85.0
GY3 50.0 91.5
GY4 25.0 95.0
GY5 12.5 97.0
GY6 5.0 98.5
GY7 2.5 99.25
表2-6,标准比色液R
对照溶液 颜色标准溶液Y 盐酸(10g/l)
R1 100.0 0.0
R2 75.0 25.0
R3 50.0 50.0
R4 37. 5 62.5
R5 25.0 75.0
R6 12.5 87.5
R7 5.0 95.0
储存
对于方法I,标准比色液在外径为12mm的无色透明中性封口的玻璃管中储存,避光。
对于方法Ⅱ,使用前直接从颜色标准液制备标准比色液。
仪器和试剂:
myreebok
第4楼2009/06/24
这个版本的我觉得比上个好一点。
(Ph. Eur. method 2.2.2)
The examination of the degree of coloration of liquids in the range brown-yellow-red is carried out by one of the 2 methods below, as prescribed in the monograph.
颜色为褐色-黄色-红色的溶液的着色程度有如下两种检查方法
A solution is colourless if it has the appearance of water R or the solvent or is not more intensely coloured than reference solution B9.
如果溶液的颜色不比水或溶剂或参比溶液B9深,那么溶液是无色的。
Method I 方法
Using identical tubes of colourless, transparent, neutral glass of 12 mm external diameter, compare 2.0 ml of the liquid to be examined with 2.0 ml of water R or of the solvent or of the reference solution (see Tables of reference solutions) prescribed in the monograph. Compare the colours in diffused daylight, viewing horizontally against a white background.
使用同种规格的无色的,透明的,中性的外径为12 mm玻璃管, 2.0 ml的测试溶液和2.0 ml的水或溶剂或方法中要求的参比溶液(见参比溶液表)比较。在散射光下,同置白色背景下,水平观察,比较颜色。
Method II 方法
Using identical tubes of colourless, transparent, neutral glass with a flat base and an internal diameter of 15 mm to 25 mm, compare the liquid to be examined with water R or the solvent or the reference solution (see Tables of reference solutions) prescribed in the monograph, the depth of the layer being 40 mm. Compare the colours in diffused daylight, viewing vertically against a white background.
使用同种规格的无色的,透明的,中性的平底的内径为15 mm ~ 25 mm的玻璃管,测试溶液和水或溶剂或方法中要求的参比溶液(见参比溶液表)比较,层深度为40 mm。在散射光下,同置白色背景下,垂直观察,比较颜色。
Reagents 溶剂
Primary solutions 原液
Yellow Solution? Dissolve 46 g of ferric chloride R in about 900 ml of a mixture of 25 ml of hydrochloric acid R and 975 ml of water R and dilute to with the same mixture. Titrate and adjust the solution to contain 45.0 mg of FeCl3,6H2O per millilitre by adding the same acidic mixture. Protect the solution from light.
黄色溶液 取46g氯化铁,加900ml的由25ml的盐酸和975ml的水组成的混合物中使溶解,加此混合物稀释至1000.0 ml。滴定并加此酸性混合物调整,使溶液中含有45.0mg/l的FeCl3,6H2O。避光保存。
Titration. Place in a 250 ml conical flask fitted with a ground-glass stopper, 10.0 ml of the solution, 15 ml of water R, 5 ml of hydrochloric acid R and 4 g of potassium iodide R, close the flask, allow to stand in the dark for 15 min and add 100 ml of water R. Titrate the liberated iodine with 0.1 M sodium thiosulphate, using 0.5 ml of starch solution R, added towards the end of the titration, as indicator.
1 ml of 0.1 M sodium thiosulphate is equivalent to 27.03 mg of FeCl3,6H2O.
滴定 在250ml的带磨砂玻璃塞的锥形瓶中,加入10.0 ml的此溶液,15 ml的水,5 ml的盐酸和4 g的碘化钾,塞上塞,避光静置15分钟,再加入100 ml的水。用0.1 M的硫代硫酸钠滴定游离碘,加入0.5ml淀粉溶液作指示剂,滴加至终点。
1ml 0.1M的硫代硫酸钠相当于27.03mg的FeCl3,6H2O
Red Solution? Dissolve 60 g of cobalt chloride R in about 900 ml of a mixture of 25 ml of hydrochloric acid R and 975 ml of water R and dilute to 1000.0 ml with the same mixture. Titrate and adjust the solution to contain 59.5 mg of CoCl2,6H2O per millilitre by adding the same acidic mixture.
红色溶液 取60g二氯化钴,加900ml由25ml的盐酸和975ml的水组成的混合物使溶解,加此混合物稀释至1000.0 ml。滴定并加此酸性混合物调整,使溶液中含有59.5 mg/l的CoCl2,6H2O
Titration. Place in a 250 ml conical flask fitted with a ground-glass stopper, 5.0 ml of the solution, 5 ml of dilute hydrogen peroxide solution R and 10 ml of a 300 g/l solution of sodium hydroxide R. Boil gently for 10 min, allow to cool and add 60 ml of dilute sulphuric acid R and 2 g of potassium iodide R. Close the flask and dissolve the precipitate by shaking gently. Titrate the liberated iodine with 0.1 M sodium thiosulphate, using 0.5 ml of starch solution R, added towards the end of the titration, as indicator. The end-point is reached when the solution turns pink.
1 ml of 0.1 M sodium thiosulphate is equivalent to 23.79 mg of CoCl2,6H2O.
滴定 在250ml的带磨砂玻璃塞的锥形瓶中,加入5.0 ml的此溶液,5.0ml的稀过氧化氢溶液和10ml的300 g/l的氢氧化钠溶液。缓慢煮沸10分钟,冷却并加入60ml的稀硫酸和2g的碘化钾。塞上塞并轻轻摇动使完全溶解。用0.1 M的硫代硫酸钠滴定游离碘,加入0.5ml淀粉溶液作指示剂,滴定至终点。溶液变为粉红色即为终点。
1ml 0.1M的硫代硫酸钠相当于23.79 mg的CoCl2,6H2O
myreebok
第5楼2009/06/24
如果哪位大大能猜出我贴出来的是哪家公司的版本,偶把整个word文档发给它额。。。
Blue Primary Solution? Dissolve 63 g of copper sulphate R in about 900 ml of a mixture of 25 ml of hydrochloric acid R and 975 ml of water R and dilute to 1000.0 ml with the same mixture. Titrate and adjust the solution to contain 62.4 mg of CuSO4, 5H2O per millilitre by adding the same acidic mixture.
蓝色原液 取63 g硫酸铜,加900ml由25ml的盐酸和975ml的水组成的混合物使溶解,加此混合物稀释至1000.0 ml。滴定并加此酸性混合物调整,使溶液中含有62.4 mg/l的CuSO4, 5H2O
Titration. Place in a 250 ml conical flask fitted with a ground-glass stopper, 10.0 ml of the solution, 50 ml of water R, 12 ml of dilute acetic acid R and 3 g of potassium iodide R. Titrate the liberated iodine with 0.1 M sodium thiosulphate, using 0.5 ml of starch solution R, added towards the end of the titration, as indicator. The end-point is reached when the solution shows a slight pale brown colour.
1 ml of 0.1 M sodium thiosulphate is equivalent to 24.97 mg of CuSO4,5H2O.
滴定 在250ml的带磨砂玻璃塞的锥形瓶中,加入10.0 ml的此溶液,50ml的水,12ml的稀乙酸和3 g的碘酸钾。用0.1 M的硫代硫酸钠滴定游离碘,加入0.5ml淀粉溶液作指示剂,滴定至终点。溶液略显浅棕色即为终点。
1 ml的0.1 M的硫代硫酸钠相当于24.97 mg的CuSO4,5H2O
Standard Solutions 标准溶液
Using the 3 primary solutions, prepare the 5 standard solutions as follows:
使用3种原液配置下列5种标准溶液:
表2.2.2.-1
标准溶液 体积(ml)
黄色原液 红色原液 蓝色原液 (10g/l盐酸)
B(棕色)
BY(棕黄色)
Y(黄色)
GY(黄绿色)
R(红色)
Reference solutions for Methods I and II 方法I 和 II使用的参比溶液
Using the 5 standard solutions, prepare the following reference solutions.
使用5种标准溶液配置参比溶液
表2.2.2-2参比溶液B
参比溶液 体积(ml)
标准溶液B (10g/l盐酸)
B1
表2.2.2-3参比溶液BY
参比溶液 体积(ml)
标准溶液BY (10g/l盐酸)
BY1
表2.2.2-4参比溶液Y
参比溶液 体积(ml)
标准溶液Y (10g/l盐酸)
Y1
表2.2.2-5参比溶液GY
参比溶液 体积(ml)
标准溶液GY (10g/l盐酸)
GY1
表2.2.2-6参比溶液R
参比溶液 体积(ml)
标准溶液R (10g/l盐酸)
R1
Storage 贮存
For Method I, the reference solutions may be stored in sealed tubes of colourless, transparent, neutral glass of 12 mm external diameter, protected from light.
方法I,参比溶液避光密封保存在无色的,透明的,外径为12 mm的中性玻璃管。
For Method II, prepare the reference solutions immediately before use from the standard solutions.
方法II,使用标准溶液制备参比溶液,临配临用。
Starch Solution ? Triturate 1.0 g of soluble starch with 5 ml of water and add, stirring continuously, to 100 ml of boiling water containing 10 mg of mercury(II) iodide. 淀粉溶液 加入5ml的水化开1.0g可溶性淀粉,边搅拌边加入100 ml含10 mg碘化汞的沸水
Complies with the following test, which should be carried out each time the reagent is used. 按照下述的试验,每次需用的试剂量。
Sensitivity to iodine? A mixture of 1 ml with 20 ml of water , about 50 mg of potassium iodide and 0.05 ml of iodine碘灵敏度:1 ml 的溶液与 20 ml的水的混合物,约50 mg的碘化钾和0.05 ml的碘
Hydrogen Peroxide Solution(100 vol)过氧化氢溶液(100 vol体积)
Strong hydrogen peroxide solution 强过氧化氢溶液
Analytical reagent grade of commerce containing about 30% w/v of H2O2.
商业分析纯,约含30% w/v of H2O2.
A colourless liquid; weight per ml, about 1.10 g.
无色液体,1.10 g/ml
dilute hydrogen peroxide solution R Hydrogen Peroxide Solution (10 vol) ? Dilute hydrogen peroxide solution 稀过氧化氢溶液(10 vol体积)
Dilute hydrogen peroxide solution (20 vol) with an equal volume of water .
用水稀释氧化氢溶液(20 vol体积)得
Sulphuric Acid, Dilute ? Add 5.5 ml of sulphuric acid to 60 ml of water , allow to cool and add sufficient water to produce 100 ml. Contains 9.8% w/v of H2SO4 (about 1M )
稀硫酸 取5.5 ml的硫酸,加入60 ml的水,放冷,加水使成100 ml. 含9.8% w/v of H2SO4 (约1M )
Acetic Acid, Dilute ? Dilute 12 g of glacial acetic acid to 100 ml with water . It contains not less than 11.5% and not more than 12.5% w/v of C2H4O2 (2M ).
稀醋酸 取12 g的冰乙酸,加水使成100 ml。含C2H4O2 (2M ).11.5% ~12.5%
wangjinxiang825
第8楼2011/12/12