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低分辨质谱能进行非靶向分析吗?

  • Ins_6e221ddb
    2024/07/11
  • 私聊

气质联用(GCMS)

  • 读了篇文献[Targeted and untargeted gas chromatography-mass spectrometry analysis of honey samples for determination of migrants from plastic packages(塑料包装蜂蜜样品中迁移物测定用靶向和非靶向气相色谱-质谱分析)],气相色谱分析采用Agilent 6890 N (Agilent, Waldbronn, Germany)气相色谱仪与配备惰性离子源的Agilent 5973四极质选谱仪进行。【文献原文:2.2. Instrumentation and software:GC analyses were performed on an Agilent 6890 N (Agilent, Waldbronn, Germany) gas chromatograph coupled to an Agilent 5973 quadrupole mass selective spectrometer equipped with an inert ion source.】在非靶向分析那写的:根据文献,包括目标分析物和其他从塑料到食物的潜在迁移物的数据库,已创建(补充数据表S2)。利用NIST和Wiley质谱文库对所研究的蜂蜜样品中的m/z离子特征进行了监测,并对其进行了鉴定。共检出13种疑似化合物。[文献原文: 3.4.2. Untargeted approach :A database including the target analytes and other potential migrants from plastic into food, based on the literature, has been created (Supplementary data Table S2). Based on their characteristic m/z ions, all these compounds were monitored in the studied honey samples using the NIST and Wiley MS libraries for their identification. A total of 13 putative compounds were found.]

    文献中用的是低分辨质谱吧?低分辨质谱能进行非靶向分析吗?但是低分辨质谱不是需要标品吗?文献就只有靶向分析的标品,非靶向分析只有数据库也行吗?
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  • symmacros

    第1楼2024/07/11

    应助达人

    低分辨质谱能可以进行非靶向分析的。能对未知物进行分析的。当然高分辨更有优势。

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  • xiaolanzi5

    第2楼2024/07/11

    应助达人

    非靶向一般都是定性,半定量。绝对定量需要根据定性结果,购买或合成标准品再定量。

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