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【求助】关于美国药典注射剂各论中 含量测定供试品溶液的配制问题

  • fuyuyingzi
    2011/06/17
  • 私聊

化学药检测

  • 美国药典注射液各论配制供试品溶液常看到
    Assay preparation 1 (where it is represented as being in a single-dose container)
    Assay preparation 2 (where the label states the quantity of ampicillin in a given volume of constituted solution)

    例如注射用氨苄西林
    Assay preparation 1 (where it is represented as being in a single-dose container)—Constitute Ampicillin for Injection in an accurately measured volume of Diluent, corresponding to the volume of solvent specified in the labeling. Withdraw all of the withdrawable contents, using a suitable hypodermic needle and syringe, and quantitatively dilute with Diluent to obtain a solution containing about 1 mg of ampicillin per mL. Use this solution promptly after preparation.

    Assay preparation 2 (where the label states the quantity of ampicillin in a given volume of constituted solution)—Constitute 1 container of Ampicillin for Injection in a volume of Diluent, accurately measured, corresponding to the volume of solvent specified in the labeling. Quantitatively dilute an accurately measured portion of the constituted solution with Diluent to obtain a solution having a concentration of about 1 mg of ampicillin per mL. Use this solution promptly after preparation.

    我翻译的是
    供试品溶液1(当以一次性剂量容器标示时)
    供试品溶液2(当以临用前溶液所含氨苄西林的量标示时)

    不过始终不清楚到底这两种剂型到底是怎么回事。实际的制剂到底是什么样情况什么时候用1,什么时候用2?
    希望有人给予解答!
  • 该帖子已被版主-加5积分,加2经验;加分理由:好,谈论美国药典,提高了版块的档次
    +关注 私聊
  • 神话

    第1楼2011/06/17

    翻译要看上下文,需要整体都译出来的

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