This overview evaluates the capabilities of mass spectrometry (MS) in combination with gas chromatography (GC) and liquid chromatography ($$lc) for the determination of a multitude of pesticides. The selection of pesticides for this assessment is based on the status of production, the existence of regulations on maximum residue levels in food, and the frequency of residue detection. GC–MS with electron impact (EI) ionization and the combination of $$lc with tandem mass spectrometers ($$lc–MS/MS) using electrospray ionization (ESI) are identified as techniques most often applied in multi-residue methods for pesticides at present. Therefore, applicability and sensitivity obtained with GC–EI–MS and $$lc–ESI–MS/MS is individually compared for each of the selected pesticides. Only for one substance class only, the organochlorine pesticides, GC-MS achieves better performance. For all other classes of pesticides, the assessment shows a wider scope and better sensitivity if detection is based on $$lc–MS.
Residue analysis of 500 high priority pesticides Better by [url=https://insevent.instrument.com.cn/t/bp]GC-MS or $$lc-MS MS[/url]
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