【求助】急求 紫外线吸收剂毒性安全数据

提供一部分数据，希望对楼主有用！


131-56-6--化学品毒性数据库

◇◇◇化学鉴别信息◇◇◇
【RTECS 编号】DJ0700000
【化学名】Benzophenone, 2,4-dihydroxy-
【CAS 登记号】131-56-6
【BEILSTEIN 参考号】1311566
【参考】4-08-00-02442 (Beilstein Handbook Reference)
【上次更新时间】199701
【引用数据项】7
【分子式】C13-H10-O3
【分子量】214.23
【维斯韦塞(氏)线的符号】QR CQ DVR
【化合物描述】Primary Irritant
【别名】 * 2,4-Dihydroxybenzofenon * 2,4-Dihydroxybenzophenone * Eastman Inhibitor DHPB * Quinsorb 010 * Syntase 100 * UF 1 * USAF DO-28 * USAF ND-54 * Uvinul 400
◇◇◇卫生公害数据◇◇◇
〖皮肤/眼睛刺激数据〗
【测试类型】Standard Draize test
【接触途径】Administration into the eye
【测试物种】Rodent - rabbit
【剂量/时间】100 mg/24HREACTION SEVERITY : Moderate
【参考】85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,652,1986
〖急性毒性数据〗
【测试类型】LD50 - Lethal dose, 50 percent kill
【接触途径】Oral
【测试物种】Rodent - rat
【剂量/时间】8600 mg/kg
【毒性作用】Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea
【参考】RPZHAW Roczniki Panstwowego Zakladu Higieny. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1950- Volume(issue)/page/year: 19,179,1968
【测试类型】LD50 - Lethal dose, 50 percent kill
【接触途径】Intraperitoneal
【测试物种】Rodent - mouse
【剂量/时间】100 mg/kg
【毒性作用】Details of toxic effects not reported other than lethal dose value
【参考】NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
【测试类型】LD50 - Lethal dose, 50 percent kill
【接触途径】Intravenous
【测试物种】Rodent - mouse
【剂量/时间】85 mg/kg
【毒性作用】Details of toxic effects not reported other than lethal dose value
【参考】BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 22,221,1964
〖其他多剂量毒性数据〗
【测试类型】TDLo - Lowest published toxic dose
【接触途径】Oral
【测试物种】Rodent - rat
【剂量/时间】54600 mg/kg/91D-I
【毒性作用】Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count
【参考】RPZHAW Roczniki Panstwowego Zakladu Higieny. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1950- Volume(issue)/page/year: 19,179,1968
◇◇◇NIOSH 标准发展和监测数据◇◇◇
【NIOSH 职业性接触鉴定数据】NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5161 No. of Facilities: 1090 (estimated) No. of Industries: 8 No. of Occupations: 20 No. of Employees: 6623 (estimated) No. of Female Employees: 981 (estimated)